ASTAXANTHIN REDUCES STEMNESS MARKERS IN BT20 AND T47D BREAST CANCER STEM CELLS BY INHIBITING EXPRESSION OF PONTIN AND MUTANT P53

Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53

Astaxanthin (AST) is a product made from marine organisms that has been used as an anti-cancer supplement.It reduces pontin expression and induces apoptosis in SKBR3, a breast cancer cell line.Using Western Cyber Tattoo Machines blotting and qRT-PCR analyses, this study revealed that in the T47D and BT20 breast cancer cell lines, AST inhibits expre

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Evolution of embryonic developmental period in the marine bird families Alcidae and Spheniscidae: roles for nutrition and predation?

Abstract Background Nutrition and predation have been considered two primary agents of selection important in the evolution of avian life history traits.The relative importance of these natural selective forces in the evolution of avian embryonic developmental period (EDP) remain poorly resolved, perhaps in part because research has tended to focus

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Prestressed elasticity of amorphous solids

Prestress in amorphous solids bears the memory of their formation and plays a profound role in their mechanical properties.Here we develop a set of mathematical tools to investigate mechanical response of prestressed systems, using stress rather than strain as the fundamental variable.This theory allows microscopic prestress to vary for the same bo

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